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Nicholas R Natale Selected Research

Isoxazoles

11/202010-N-heterocylic aryl-isoxazole-amides (AIMs) have robust anti-tumor activity against breast and brain cancer cell lines and useful fluorescence properties.
8/2009Bis-anthracenyl isoxazolyl amides have enhanced anticancer activity.
2/2009Design, synthesis and biological evaluation of a novel class of anticancer agents: anthracenylisoxazole lexitropsin conjugates.

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Nicholas R Natale Research Topics

Disease

3Neoplasms (Cancer)
11/2020 - 02/2009
1Glioblastoma (Glioblastoma Multiforme)
01/2022
1Stroke (Strokes)
04/2021
1Ischemic Stroke
04/2021
1Ischemia
04/2021
1Brain Neoplasms (Brain Tumor)
11/2020
1Substance-Related Disorders (Drug Abuse)
01/2012
1Glioma (Gliomas)
08/2009
1Alzheimer Disease (Alzheimer's Disease)
01/2006

Drug/Important Bio-Agent (IBA)

3IsoxazolesIBA
11/2020 - 02/2009
3AmidesIBA
11/2020 - 02/2009
2Glutamic Acid (Glutamate)FDA Link
01/2012 - 01/2006
1diphenyl (biphenyl)IBA
01/2022
1FSC 231IBA
04/2021
1CalciumIBA
04/2021
1AMPA Receptors (AMPA Receptor)IBA
04/2021
1Neurotransmitter Agents (Neurotransmitter)IBA
01/2012
1Cystine (L-Cystine)IBA
01/2012
1Carrier Proteins (Binding Protein)IBA
01/2006
1N-Methylaspartate (NMDA)IBA
01/2006
1Memantine (Namenda)FDA Link
01/2006

Therapy/Procedure

1Therapeutics
04/2021